Nematic liquid crystal as a representative soft matter is an excellent model system to study the structures and topological defects of partially ordered matter. Our group at UNIST pushes frontiers of this field by investigating confined lyotropic chromonic liquid crystals (LCLCs) with unique elastic properties: the very small twist elastic modulus and large saddle-splay modulus. In this talk at HKUST, I will introduce a series of our experiments introducing new director configurations and defects of (chiral) LCLCs in cylindrical confinements, which provide two different principal curvatures and surface anchoring condition on demand. I will wrap up this talk by sharing our works exploring LCs in various confinements and other fields of soft matter.